Category: Analytic Chemistry

Handbook of Modern Pharmaceutical Analysis (Separation by Satinder Ahuja,Stephen Scypinski

By Satinder Ahuja,Stephen Scypinski

Handbook of contemporary Pharmaceutical Analysis, Second Edition, synthesizes the complicated learn and up to date alterations within the field, while overlaying the techniques and technology required for ultra-modern laboratories. The work integrates approach, case reports, methodologies, and implications of recent regulatory buildings, offering entire assurance of caliber coverage from the purpose of discovery to the purpose of use.

  • Treats pharmaceutical research (PA) as an critical companion to the drug improvement strategy instead of as a carrier to it
  • Covers strategy improvement, validation, choice, trying out, modeling, and simulation experiences mixed with complex exploration of assays, impurity trying out, biomolecules, and chiral separations
  • Features detailed coverage of QA, ethics, and regulatory advice (quality by means of layout, sturdy production practice), in addition to high-tech methodologies and applied sciences from "lab-on-a-chip" to LC-MS, LC-NMR, and LC-NMR-MS

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Process Chromatography: A Guide to Validation by Gail K. Sofer,L. E. E. Nystrom

By Gail K. Sofer,L. E. E. Nystrom

learn and improvement into organic items for healing use has elevated dramatically over the past 10 years. With this, strict regulatory standards were imposed by means of gurus resembling the U.S. nutrition & Drug management, in order that this day validation has turn into a key factor within the biopharmaceutical industry.
This concise publication addresses validation matters within the chromatography of biotherapeutics. It covers technique layout, qualification and validation, together with an outline of analytical ideas commonplace within the validation of procedures. A concluding part reviews on product changeover and provides 4 case studies.

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Passive Sampling Techniques in Environmental Monitoring: 48 by Richard Greenwood,Graham Mills,Bran Vrana

By Richard Greenwood,Graham Mills,Bran Vrana

tracking pollution in air, soil and water is a regimen requirement within the place of work, and within the wider surroundings. Passive samplers delivers a consultant photo of degrees of toxins over a time period from days to months via measuring the typical concentrations to which they've been uncovered. Air displays are generic, for example to degree the publicity of staff to unstable compounds, but additionally for tracking the destiny of pollution within the surroundings. Passive sampling units are actually becomining more and more used to watch toxins in rivers, coastal waters and flooring water the place illness effects from resources similar to family and commercial discharges, and using agrochemicals.
Passive Sampling concepts in Environmental Monitoring presents a well timed selection of info on a collection of suggestions that support display screen the standard of air, floor and floor waters. Passive sampling grants a cheap technique of acquiring a consultant photograph of caliber over a time period, even the place degrees of toxins vary because of discontinuous discharges or seasonal software of chemical compounds equivalent to insecticides. contemporary alterations in laws have elevated the strain to acquire higher info than that supplied by means of classical rare spot sampling.
Brought jointly in a single resource, this publication appears to be like on the functionality of a number units for the passive sampling of metals, and of non-polar and polar natural chemical compounds in air and in water. The strengths and weaknesses and the variety of applicability of the expertise are considered.

* finished evaluate of passive sampling - overlaying air, water and majority of accessible applied sciences in a single volume
* Chapters written via overseas professional specialists
* Covers thought and functions, delivering history details and instructions to be used within the field

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Surface and Thin Film Analysis: A Compendium of Principles, by Gernot Friedbacher,Henning Bubert

By Gernot Friedbacher,Henning Bubert

Surveying and evaluating all strategies appropriate for functional purposes in floor and skinny movie research, this moment version of a bestseller is an important consultant to this sizzling subject in nano- and floor expertise. This new publication has been revised and up-to-date and is split into 4 components - electron, ion, and photon detection, in addition to scanning probe microscopy. New chapters were extra to hide such suggestions as SNOM, FIM, atom probe (AP),and sum frequency iteration (SFG). Appendices with a precis and comparability of options and an inventory of kit providers make this ebook a fast reference for fabrics scientists, analytical chemists, and people operating within the biotechnological industry.

From a assessment of the 1st version (edited by means of Bubert and Jenett)
"... an invaluable resource..."
(Journal of the yank Chemical Society)

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Characterization of Compounds in Solution - Theory and by William H. Streng

By William H. Streng

Scientists from many disciplines require making observations that are established upon the habit of compounds in resolution. This levels from components in geography, akin to oceanography, to parts in chemistry, resembling chromatography, to components in biology, corresponding to pharmacology. traditionally, details will be acquired through looking at a reaction for a given set of stipulations after which the stipulations will be replaced and a brand new reaction received. during this strategy there will be little attempt made to truly know the way a compound used to be behaving in answer yet relatively simply the reaction used to be famous. figuring out the habit of compounds in resolution is important to figuring out their habit in organic structures. This has develop into more and more vital over the last two decades as an figuring out of the biochemistry concerning human ailment has turn into larger understood. the improvement of the pharmaceutical and the necessity to speedily reveal huge numbers of compounds has made scientists within the region of drug improvement conscious that the pharmacological task of compounds could be estimated by means of understanding their resolution actual chemical homes. this isn't to assert particular drug-active website interplay might be anticipated yet quite a prediction should be made even if a compound might be absorbed, transported, or dispensed inside a physiological method in one of these manner that an interplay can occur.

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Molecular Fluorescence: Principles and Applications by Bernard Valeur,Mário Nuno Berberan-Santos

By Bernard Valeur,Mário Nuno Berberan-Santos

This moment variation of the well-established bestseller is totally up-to-date and revised with nearly 30 % extra fabric, together with new chapters on functions, which has obvious the main major advancements.

The accomplished review written at an introductory point covers primary features, ideas of instrumentation and functional functions, whereas delivering many necessary counsel.

For photochemists and photophysicists, actual chemists, molecular physicists, biophysicists, biochemists and biologists, teachers and scholars of chemistry, physics, and biology.

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Laborpraxis Band 1: Einführung, Allgemeine Methoden (German by aprentas

By aprentas

Das vierbändige Standardwerk für die grundlegende praktische Arbeit im chemisch-pharmazeutischen hard work mit Schwerpunkt Synthesemethoden, Chromatographie und Spektroskopie liegt jetzt in der 6. völlig neu überarbeiteten Auflage vor. Es dient Berufseinsteigern als breit angelegtes Lehrmittel und erfahrenen Fachkräften als Nachschlagewerk mit übersichtlich dargestellten theoretischen Grundlagen und konkreten, erprobten Anwendungsideen.

Die theoretischen Grundlagen für jedes Kapitel sind intestine lesbar abgefasst und unterstützen das Verständnis für praktische Arbeiten und Gerätefunktionen. Zu jedem Kapitel gibt es Hinweise auf vertiefende und weiterführende Literatur. Arbeitssicherheit und –hygiene sowie die zwölf Prinzipien der nachhaltigen Chemie finden neben den entsprechenden Kapiteln Beachtung. Die im Buch erwähnten praktischen Grundlagen gründen auf Gegebenheiten in der chemisch-pharmazeutischen Industrie in der Schweiz. Sie finden im gesamten deutschsprachigen Raum Anwendung, auch in verwandten Arbeitsgebieten wie biochemischen, klinischen, werkstoffkundlichen oder universitären Laboratorien.

Die Laborpraxis eignet sich für den Einsatz in der Grund- und in der Weiterbildung von Fachpersonal. Der Inhalt entspricht den aktuellen Anforderungen der Bildungsverordnung und des Bildungsplanes zum Beruf Laborantin / Laborant mit eidgenössischem Fähigkeitszeugnis (EFZ), welche vom Staatssekretariat für Bildung, Forschung und Innovation (SBFI) in Bern verordnet wurden. Damit steht den Lernenden eine gute Grundlage für die Vorbereitung auf das Qualifikationsverfahren (QV) zur Verfügung; Expertinnen und Experten stützen ihre persönlichen Vorbereitungsarbeiten und ihre fachlichen Beurteilungen auf dieses Buch.

Band 1 und Band 2 behandeln ausführlich die Grundlagen der Laborarbeit und ausgewählte Messtechniken. Band three ist auf präparative und analytische Trennungsmethoden, Band four auf nasschemische und spektroskopische Analysemethoden fokussiert. Sowohl konventionelle Methoden als auch modernste Techniken finden Erwähnung. Der Fokus auf beständig gültigen Prinzipien erlaubt auch neue, nicht erwähnte Techniktrends zu verstehen sowie die tägliche Arbeit im chemisch-pharmazeutischen hard work zu reflektieren.

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Handbook for the Chemical Analysis of Plastic and Polymer by Michael Bolgar,Jack Hubball,Joseph Groeger,Susan Meronek

By Michael Bolgar,Jack Hubball,Joseph Groeger,Susan Meronek

Polymers have unquestionably replaced the area via many items that increase our lives. in spite of the fact that, ingredients used to change the final features of those fabrics is probably not totally disclosed or understood. those ingredients may perhaps current attainable environmental and health and wellbeing risks. it is very important display screen customer items for those compounds utilizing top quality reference fabrics and constant analytical techniques.

The instruction manual for the Chemical research of Plastic and Polymer ingredients, moment variation provides the required instruments for chemists to acquire a extra whole directory of additions found in a selected polymeric matrix. it truly is designed to function a useful resource for these tracking a polymer/plastic fabric for regulatory or inner compliance. It additionally is helping analysts to properly determine the advanced nature of the fabrics which have been extra to the polymer/plastic.

With 50 extra compounds, this moment version approximately doubles the variety of ingredients in different different types, together with processing aids, antistatic compounds, mildew free up items, and blowing brokers. It incorporates a directory that may be cross-referenced by means of alternate identify, chemical identify, CAS quantity, or even key mass unit ions from the GC/MS run.

Addressing ingredients from an analytical perspective, this accomplished guide is helping readers determine the ingredients in plastics. this knowledge can be utilized to evaluate compliance with laws issued by means of the FDA, US EPA, european, and different agencies.

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Nondestructive Evaluation of Food Quality: Theory and by Shyam N. Jha

By Shyam N. Jha

quite a few works on non-destructive checking out of nutrients caliber were stated within the literature. ideas comparable to close to InfraRed (NIR) spectroscopy, color and visible spectroscopy, digital nostril and tongue, laptop imaginative and prescient (image analysis), ultrasound, x-ray, CT and magnetic resonance imaging are essentially the most utilized for that objective and are defined during this e-book. points equivalent to theory/basics of the options, useful functions (sampling, experimentation, info research) for assessment of caliber attributes of meals and a few fresh works suggested in literature are awarded and mentioned. This e-book is very fascinating for brand new researchers in nutrients caliber and serves as an up-to-date state of the art document for these already conversant in the field.

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Introduction to Quantitative Ultramicroanalysis by I. M. Korenman

By I. M. Korenman

creation to Quantitative Ultramicroanalysis has been compiled at the foundation of news released via a variety of authors. It doesn't declare to supply an exhaustive remedy of ultramicroanalysis, however it summarizes info at the topic and comparable experimental tools and strategies, newly designed considered necessary apparatus, and so forth. a number of methods are defined that have proved powerful in interpreting minute quantities of pattern. The weighing of super small gadgets is taken care of such a lot commonly, as are the titration and colorimetry of options. The apparatus utilized in ultramicroanalysis, as well as its minute measurement, is of a hugely really good layout. those distinct good points, in addition to many of the easier micromanipulators, are mentioned within the comparable chapters.

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