Hydrophilic Interaction Chromatography: A Guide for by Bernard A. Olsen,Brian W. Pack

By Bernard A. Olsen,Brian W. Pack

Discover tips to use HILIC to investigate and higher comprehend polar compounds

An more and more renowned analytical process, hydrophilic interplay chromatography (HILIC) has the power to preserve and separate polar compounds which are usually tough to research by way of reversed-phase high-performance liquid chromatography (HPLC) or different analytical tools. delivering a finished evaluation, this publication allows readers to advance a basic knowing of the way HILIC works after which observe that wisdom to enhance and enforce various functional applications.

Hydrophilic interplay Chromatography starts with discussions of HILIC retention mechanisms, desk bound stages, and common procedure improvement. This units the basis for the book's broad assurance of functions. The authors handle exact separation demanding situations for bioanalytical, environmental, pharmaceutical, and biochemical purposes. additionally, there's a thorough dialogue of HILIC in two-dimensional chromatography.

With contributions from major analytical scientists who've huge event in HILIC in addition to HPLC, Hydrophilic interplay Chromatography serves as a pragmatic advisor for researchers, featuring:

  • Detailed examples of HILIC equipment and improvement approaches
  • Thorough motives of retention mechanisms and the effect of desk bound part and cellular section homes on separations
  • Step-by-step tips for constructing effective, delicate, and powerful HILIC methods
  • References to the first literature on the finish of every chapter

Hydrophilic interplay Chromatography is written for scientists who use or boost analytical equipment for the separation of polar compounds. specifically, those researchers will notice how HILIC can be utilized to research and higher comprehend the composition of pharmaceutical, bioanalytical, biochemical, chemical, foodstuff, and environmental samples.

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