Molekulare Mechanismen der Zellalterung und ihre Bedeutung by Behl,Ziegler,Christine Ziegler

By Behl,Ziegler,Christine Ziegler

Dieses Buch führt in die wichtigsten Theorien des Alterns ein; es konzentriert sich auf Telomere, DNA-Schädigung, oxidativen tension, die Rolle der Nährstoffversorgung bzw. -erkennung, das Zusammenspiel von Genen und Umwelt (Epigenetik) und die Proteinhomöostase und stellt einige Gene vor, die die Lebensdauer in Modellorganismen zu verändern in der Lage sind. Indem es die verschiedenen das Altern bestimmenden Faktoren mit Erkrankungen des Menschen verknüpft, sucht das Buch ihre vielfältigen Wechselbeziehungen und Abhängigkeiten aufzuzeigen und zu einer molekularen Matrix des Alterns zusammenzuführen. Von diesem Buch werden alle profitieren, die sich einen profunden Überblick über die Mechanismen der Zellalterung und ihre Verknüpfung mit altersassoziierten Erkrankungen des Menschen verschaffen wollen.

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