By F. Javier Alvarez-Leefmans,Eric Delpire
- The first complete publication at the constitution, molecular biology, mobilephone body structure, and position in ailments of chloride transporters / channels within the anxious method in nearly 20 years
- Chloride is the main ample unfastened anion in animal cells. THis publication summarizes and integrates for the 1st time the $64000 study of the earlier twenty years that has proven that Cl- channels and companies play key useful roles in GABA- and glycine-mediated synaptic inhibition, neuronal progress and improvement, extracellular potassium scavenging, sensory-transduction, neurotransmitter uptake and mobile quantity control
- The first publication that systematically discusses the results of disruption of Cl- homeostasis in neurons which underlies pathological stipulations akin to epilepsy, deafness, imbalance, mind edema and ischemia, discomfort and neurogenic inflammation
- Spanning issues from molecular constitution and serve as of providers and channels serious about Cl- shipping to their position in a number of diseases
- Involves all the best researchers within the field
- Includes an intensive introductory part that covers uncomplicated thermodynamic and kinetics features of Cl- shipping, in addition to present equipment for learning Cl- legislation, spanning from fluorescent dyes in unmarried cells to knock-out types to make the booklet to be had for a becoming inhabitants of graduate scholars and postdocs coming into the field
Read Online or Download Physiology and Pathology of Chloride Transporters and Channels in the Nervous System: From Molecules to Diseases PDF
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