RNA Turnover in Eukaryotes: Nucleases, Pathways and Analysis by Lynne E. Maquat,Megerditch Kiledjian

By Lynne E. Maquat,Megerditch Kiledjian

particular complexes of protein and RNA perform many crucial organic capabilities, together with RNA processing, RNA turnover, RNA folding, in addition to the interpretation of genetic info from mRNA into protein sequences. Messenger RNA (mRNA) decay is now rising as an enormous regulate element and an important contributor to gene expression. carrying on with id of the protein elements and cofactors, and mRNA instability components answerable for mRNA decay let researchers to construct a entire photo of the hugely orchestrated procedures fascinated about mRNA decay and its regulation.

  • Covers the nonsense-mediated mRNA decay (NMD) or mRNA surveillance pathway
  • Expert researchers introduce the main complicated applied sciences and methods to spot mRNA processing, delivery, localization and turnover, that are significant to the method of gene expression
  • Offers step by step lab directions, together with valuable apparatus and reagents

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