Sex and Gender Differences in Pharmacology: 214 (Handbook of by Vera Regitz-Zagrosek

By Vera Regitz-Zagrosek

this can be the first actual e-book to house intercourse and gender changes in drug treatment - an more and more well-known clinical desire. It begins with an summary on S/G in scientific syndromes and a documentation of the scientific and socioeconomic harm attributable to gender particular hostile drug results. half I covers S/G alterations in pharmacokinetics. Researchers can be chuffed by way of the precise dialogue of the mechanisms of S/G transformations in drug results that represents leading edge technology and contains interplay of gear with intercourse hormones, genomic and epigenetic mechanisms. It additionally covers S/G in drug improvement, in animal types and medical improvement and S/G in drug prescriptions. half II objectives S/G alterations in drug results in cardiovascular, pulmonary, CNS, neuromuscular, neuropsychiatric and metabolic ailments, in melanoma, irritation, and rheumatic ailments, in bacterial and retroviral infections, thrombosis, embolism. New medicinal drugs might be discussed.

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