Therapeutic Peptides and Proteins: Formulation, Processing, by Ajay K. Banga

By Ajay K. Banga

There are greater than 500 biopharmaceuticals out there, together with greater than 2 hundred healing proteins, making biologics the quickest turning out to be region within the biopharmaceutical industry. those items contain greater than forty monoclonal antibodies, for symptoms starting from remedy or mitigation of assorted varieties of melanoma to rheumatoid arthritis.

The medical software of those healing peptides and proteins is proscribed via numerous difficulties, similar to loss of actual and chemical balance or the shortcoming of fascinating attributes for sufficient absorption or distribution. hence, as those healing peptides and proteins are made to be had, will probably be necessary to formulate those medicines into secure, solid, and efficacious supply platforms. The pharmaceutical scientist serious about this attempt must name upon the information of a number of disciplines, resembling pharmaceutics, medicinal chemistry, biochemistry, microbiology, and chemical engineering and wishes to maintain abreast with the newest learn within the released literature.

Therapeutic Peptides and Proteins: formula, Processing, and supply structures, 3rd variation provides a entire assessment of the sphere for scientists in and academia and for college kids, whereas additionally supplying sensible info at the demanding situations dealing with the formula and supply points of those specified macromolecules. specifically, the e-book:

  • Explains how recombinant DNA innovations now let us produce healing proteins in a commercially manageable form

  • Discusses the actual and chemical pathways of peptide and protein degradation

  • Includes an in depth dialogue of protein formula and lyophilization

  • Overviews the pharmacokinetic features of healing peptides and proteins and discusses managed supply platforms for parenteral management, together with microsphere formulations

  • Discusses learn growth on oral, transdermal, mucosal, and topical supply platforms discusses transdermal and topical delivery

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